Abstract: The influence of sand milling times on the quality of titanium dioxide （TiO₂） initial product was investigated by horizontal sand mill,using roll milling TiO₂ product as raw material and zirconia beads with different sizes as grinding media. The results show that with increase of sand milling times the pH and viscosity of the slurry are not changed substantially,particle size D₅₀ decreases and the ratio of particles with size ≤1 μm increases gradually. Meanwhile,the length-diameter value of particles in the slurry decreases slowly with the degree of sphericity gradually improved,the quantity and size of the aggregates decreased,and the value of whiteness L and brightness for the obtained TiO₂ increased step by step. TiO₂ initial product with more uniform size distribution,higher value of whiteness and brightness can be obtained using 0.4mm zirconia beads,compared with those of the product prepared by 0.6 mm and 1.8 mm zirconia beads.