Abstract: The experiments of refining titanium tetrachloride using different fatty acids were carried out,and the samples of purified titanium tetrachloride and tailing slag for vanadium removal were analyzed.The results show that with saturated fatty acids as reagent the vanadium removal efficiency is lower and the tailing slag has an excellent dispersibility. In addition,the length of carbon chain of saturated fatty acids scarcely affects the vanadium removal efficiency. The efficiency of vanadium removal by unsaturated fatty acids owning the same carbon chain length with saturated fatty acids,is more higher than that of saturated fatty acids,while the slurry for vanadium removal is more viscous and prone to agglomeration. Using mixed fatty acids as the reagent can not only guarantee the vanadium removal efficiency but also obtain the tailing slag with excellent dispersibility.