Abstract: According to the characteristic of titanium slag produced with ilmenite concentrate in Panzhihua as raw material that the content of calcium and magnesium impurities is high but the TiO₂ concentration is low,the analysis for the critical control point in process of melting salt chlorination with those titanium slags was carried out. The process control of melting salt chlorination was studied and the effects on the quality and cost of crude TiCl₄ were analyzed and compared,with titanium slags respectively containing 74% and 78% TiO₂ as raw materials. It is indicated that with the titanium slags mentioned above as raw materials the content of TiO₂ and C in the melting salt should be controlled at about 3%,and the content of solid impurities in circulating mud should be 200 g/L or so. With the titanium slag containing 74% TiO₂ as raw material,the temperature of melting salt and inlet gas for dust chamber is decreased by 30~50 ℃,and the consumption of petroleum coke and NaCl,amount of waste salts and collected sludge increase while the contents of solid impurities,VOCl₃,SiCl₄,FeCl₃ in crude TiCl₄ keep at a lower level,compared to those in the process with the titanium slag containing 78% TiO₂ as raw material. Furthermore,the cost for production of crude TiCl₄ decreases by 5%~10% using titanium slag with 74% TiO₂,comparing to that with titanium slag containing 78% TiO₂ as raw material.